NPR logoNanoprobes was founded to develop the most sensitive reagents and technology for detecting biological molecules. Our unique gold labeling technology uses chemically cross-linked metal clusters and nanoparticles as labels.Unlike conventional immunogold probes, in which colloidal gold particles are electrostatically adsorbed to antibodies and proteins, our gold labels are uncharged molecules which are cross-linked to specific sites on biomolecules. This gives our probes a range and versatility which is not available with colloidal gold.

 Our labels can be attached to any molecule with a reactive group -- proteins, peptides, oligonucleotides, small molecules and lipids -- for detection and localization. Other labels can be combined with our gold labels; our unique FluoroNanogold probes combine Nanogold® and fluorescein into a single probe for imaging a specimen both by fluorescence and electron microscopy.



Conjugates with 1.4 nm Nanogold             Histadine (His) Tag Labeling
Enhancement / Developers                          Magnetic nanoparticles
EnzMet™ ultra-sensitive                                Reagents with Nanogold®
Gold Nanoparticles                                        Xray Contrast Agents